3000mg hydrocodone

Hydrocodone bitartrate is an opioid analgesic and antitussive and occurs as fine, white crystals or as a crystalline powder, 3000mg hydrocodone. It is affected by light. The chemical name is: It has the following structural formula: Most hydrocodone these involve the central nervous system and smooth muscle. The precise mechanism of action 3000mg hydrocodone and other opiates is not known, although it is believed to relate to the existence of opiate receptors in the central nervous system.

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In addition to analgesia, narcotics may produce drowsiness, 3000mg hydrocodone, changes in mood and mental clouding, 3000mg hydrocodone. The analgesic action of acetaminophen involves peripheral influences, but the 3000mg mechanism is as yet undetermined.

Antipyretic activity is mediated through hypothalamic heat regulating centers, 3000mg hydrocodone. Acetaminophen inhibits prostaglandin synthetase, 3000mg hydrocodone. Therapeutic doses of acetaminophen have hydrocodone effects on the cardiovascular or respiratory hydrocodone however, toxic doses may cause circulatory failure and rapid, shallow breathing. Pharmacokinetics The 3000mg of the individual components is described below. 3000mg Following a 10 mg oral dose of hydrocodone administered to five adult male subjects, 3000mg hydrocodone, the mean peak concentration was Maximum serum levels were achieved at 1.

Acetaminophen Hydrocodone is rapidly 3000mg from the gastrointestinal tract and is distributed throughout most body tissues. The plasma half-life is 1.

3000mg of acetaminophen is principally by liver metabolism conjugation and subsequent hydrocodone excretion of metabolites. Patients known to be hypersensitive to other opioids may exhibit cross-sensitivity to hydrocodone. WARNINGS Respiratory Depression At high doses or in sensitive patients, hydrocodone may produce dose-related respiratory depression by acting directly on the brain hydrocodone respiratory center.

Hydrocodone also affects the center that controls respiratory rhythm, 3000mg may produce irregular and periodic breathing. Head Injury and Increased Intracranial Pressure The respiratory depressant effects of narcotics and their capacity to elevate cerebrospinal fluid pressure may be markedly exaggerated in the presence of head injury, 3000mg hydrocodone, other intracranial lesions or a preexisting increase in intracranial pressure. Furthermore, narcotics produce adverse reactions which may obscure the clinical course of patients with head injuries.

Acute Abdominal Conditions The administration of narcotics may obscure the diagnosis or clinical course of patients with acute abdominal conditions. Opioid agonists have the potential for being abused and are sought by abusers and people with addiction disorders, and are subject to diversion.

The usual precautions should be observed and the possibility of respiratory depression should be kept in mind. Cough Hydrocodone Hydrocodone suppresses the cough reflex; as with all narcotics, caution should be exercised when VICODIN Tablets are used postoperatively and in patients with pulmonary disease.

Alcohol 3000mg other CNS depressants may produce an additive CNS depression, buying doxycycline peru taken with this combination product, 3000mg hydrocodone, and should be avoided. Hydrocodone may be habit forming. Patients should take the drug only for as long as it is prescribed, in the amounts prescribed, 3000mg hydrocodone, and no more frequently than prescribed. When combined therapy is contemplated, the dose of one or both agents should be reduced.

The use of MAO inhibitors 3000mg tricyclic hydrocodone with hydrocodone preparations may increase the hydrocodone of either the antidepressant or percocet skin disorder. Carcinogenesis, 3000mg hydrocodone, Mutagenesis, Impairment of Fertility No adequate studies have been conducted in animals to determine whether hydrocodone or acetaminophen have a potential for carcinogenesis, mutagenesis, or impairment of fertility.

Pregnancy Teratogenic Effects Pregnancy Category C There are no adequate and well-controlled studies in pregnant women, 3000mg hydrocodone.

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Nonteratogenic Effects Babies born to mothers who have been taking opioids regularly prior to delivery will be physically dependent. The withdrawal signs include irritability and excessive crying, tremors, hyperactive reflexes, increased respiratory rate, increased stools, 3000mg hydrocodone, sneezing, yawning, vomiting, 3000mg hydrocodone, and fever, 3000mg hydrocodone.

The intensity hydrocodone the hydrocodone does not always correlate with the hydrocodone of maternal opioid use or dose. There is no consensus on the best method of managing withdrawal. Labor and 3000mg As with all narcotics, administration of VICODIN Tablets to the mother shortly before delivery may result in some hydrocodone of respiratory depression in the newborn, especially if higher doses 3000mg used, 3000mg hydrocodone.

Nursing Mothers Acetaminophen is hydrocodone in breast 3000mg in small amounts, 3000mg hydrocodone, but the significance of its effects on nursing infants is not known. It is not known whether hydrocodone is 3000mg in human milk, 3000mg hydrocodone. Because many drugs are excreted in human 3000mg and because of the potential for serious adverse reactions in nursing infants from hydrocodone and acetaminophen, a decision should be made whether 3000mg discontinue nursing or to discontinue the drug, taking into account the importance of hydrocodone drug to the mother.

Pediatric Use Safety and effectiveness in the pediatric population have not been established, 3000mg hydrocodone. Geriatric Use Clinical studies of VICODIN hydrocodone bitartrate 5 mg and acetaminophen mg did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.

3000mg Other reported clinical experience has not identified differences in responses between the hydrocodone and younger patients. In general, 3000mg hydrocodone, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing hydrocodone, reflecting the 3000mg frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy, 3000mg hydrocodone. Hydrocodone and best buy nizoral shampoo major metabolites of acetaminophen are known to be substantially hydrocodone by the kidney.

Because elderly patients are more likely to have decreased renal function, hydrocodone should be taken in dose selection, and it may be useful to monitor renal function. Hydrocodone may cause confusion and over-sedation in the elderly; elderly patients generally 3000mg be started on low doses of hydrocodone bitartrate and acetaminophen tablets and observed closely.

These effects seem to be more prominent in ambulatory than in nonambulatory patients and some of these adverse reactions may 3000mg alleviated if the patient lies down. Other adverse reactions include: Central Nervous System Drowsiness, mental clouding, lethargy, 3000mg hydrocodone, impairment of hydrocodone and physical performance, 3000mg hydrocodone, anxiety, fear, 3000mg hydrocodone, dysphoria, psychic dependence, mood changes, 3000mg hydrocodone.

Genitourinary System Hydrocodone spasm, 3000mg hydrocodone, spasm of vesical sphincters and urinary retention have been reported with opiates.

Respiratory Depression Hydrocodone bitartrate may produce 3000mg respiratory depression by acting directly on the brain stem respiratory center. Special Senses Cases 3000mg hearing impairment or permanent loss have been reported predominantly in patients with chronic 3000mg. Dermatological Hydrocodone rash, pruritus, 3000mg hydrocodone.

The following adverse drug events may be borne in mind as potential effects of acetaminophen: Addiction is a primary, chronic, neurobiologic disease, with genetic, psychosocial, 3000mg hydrocodone, and environmental factors influencing its development and manifestations.

DESCRIPTION

It is characterized by behaviors that include one 3000mg more of the following: Drug addiction is a treatable disease utilizing a multidisciplinary approach, 3000mg hydrocodone, but relapse is common.

Abuse and addiction are separate and distinct from physical dependence and tolerance. Physical dependence usually assumes clinically significant dimensions only after several weeks of continued opioid use, although a mild degree of 3000mg dependence may develop after a few days of opioid therapy.

Tolerance, in which increasingly large 3000mg are required in order to produce the same degree of analgesia, is manifested initially by a shortened duration of hydrocodone effect, and subsequently by decreases in the intensity of analgesia. The rate of development of tolerance varies among patients.

Physicians should be aware that abuse of opioids can occur in the absence of true addiction and is characterized by misuse for 3000mg purposes, often in combination with other psychoactive substances, 3000mg hydrocodone.

Record-keeping of prescribing information, including quantity, frequency, 3000mg hydrocodone, and renewal requests is strongly advised. Proper assessment of the patient, 3000mg hydrocodone, proper prescribing practices, periodic re-evaluation hydrocodone therapy, 3000mg hydrocodone, and proper dispensing and hydrocodone are appropriate measures that hydrocodone to limit abuse of opioid drugs. In severe overdosage, 3000mg hydrocodone, apnea, 3000mg collapse, cardiac arrest and death may occur, 3000mg hydrocodone.

Acetaminophen In acetaminophen 3000mg Renal tubular necrosis, hypoglycemic coma, and thrombocytopenia may also occur, 3000mg hydrocodone. Early symptoms following a potentially hepatotoxic overdose may include: Clinical and laboratory evidence of hepatic toxicity hydrocodone not be apparent until 48 to 72 ranitidine price uk post-ingestion. Treatment A single or multiple overdose with hydrocodone and acetaminophen is a potentially lethal polydrug hydrocodone, and consultation with a regional hydrocodone control center is recommended.

Immediate treatment includes 3000mg of cardiorespiratory function and measures to reduce drug absorption.

Vomiting should be induced mechanically, or with syrup of ipecac, 3000mg hydrocodone, if the patient is alert adequate pharyngeal and laryngeal reflexes, 3000mg hydrocodone.

The first dose should be accompanied by an appropriate cathartic, 3000mg hydrocodone. If repeated doses are used, hydrocodone cathartic might be included hydrocodone alternate doses as required. Hypotension is usually hypovolemic and should respond to fluids. Vasopressors and other supportive hydrocodone should be employed as indicated. A cuffed endo-tracheal tube should be inserted before gastric lavage of the unconscious patient and, when necessary, to provide assisted respiration.

Meticulous attention should be given to maintaining adequate pulmonary ventilation. In severe cases of intoxication, 3000mg hydrocodone, peritoneal dialysis, 3000mg hydrocodone, or preferably hemodialysis may be considered. 3000mg hypoprothrombinemia occurs due to acetaminophen overdose, 3000mg hydrocodone, vitamin K should be administered intravenously.

Naloxone, an 3000mg antagonist, can reverse respiratory depression and coma associated with opioid overdose. Since the duration of action of hydrocodone may exceed that of the naloxone, the patient should be kept under continuous surveillance and repeated doses of the antagonist should be administered as needed to maintain adequate respiration. An opioid antagonist should not 3000mg administered in the absence of clinically significant respiratory or cardiovascular hydrocodone.

Serum acetaminophen levels should 3000mg obtained, since levels four or more hours following ingestion help predict acetaminophen toxicity. Hydrocodone not await acetaminophen assay results before initiating treatment. Hepatic enzymes should be obtained initially, 3000mg hydrocodone, and repeated at hour intervals. The toxic dose for adults for acetaminophen is 10 g. However, it should be kept in mind that tolerance to street price percocet can develop with continued use and that the incidence of untoward effects is dose related, 3000mg hydrocodone.

Hydrocodone usual adult dosage is one or 3000mg tablets every four to six hours as needed for 3000mg. The total daily dosage should not 3000mg 8 tablets. Bottles of Hydrocodone Dispense in a tight, light-resistant container as defined in the USP. Do not accept if sealed blister unit has been broken or opened, 3000mg hydrocodone.